CALITHERA BIOSCIENCES INC

Gainers Sotera Health Company (NASDAQ: SHC) shares jumped 92% to $16.59 after the company announced its subsidiaries have reached agreements to settle the Ethylene Oxide cases pending against Sterigenics. Sterigenics will pay the company $408 million to settle the claims. Party City Holdco Inc. (NYSE: PRTY) gained 54% to $0.3193 following an Axios report suggesting The Franchise Group could be looking at acquiring the company. Panbela Therapeutics, Inc. (NASDAQ: PBLA) shares rose 51.1% to $0.1224 after gaining 4% on Monday. VYNE Therapeutics Inc. (NASDAQ: VYNE) climbed 50.5% to $0.2892 after the company announced the first vitiligo patient was dosed in a Phase 1a/b clinical trial of VYN201. Elys Game Technology, Corp. (NASDAQ: ELYS) jumped 49.5% to $0.6276. Boxed, Inc. (NYSE: BOXD) gained 36.6% to $0.5191 after the company announced its Spresso Saas modular solution platform is now available on Google Cloud. Biora Therapeutics, Inc. (NASDAQ: BIOR) rose 35% to $2.85. HC Wainwright & Co. maintained Biora Therapeutics with a Buy. DermTech, Inc. (NASDAQ: DMTK) shares climbed 32.6% to $2.88 after DermTech announced the foundational assay of its DermTech Melanoma Test (DMT) is recommended for coverage by TRICARE. DatChat, Inc. (NASDAQ: DATS) gained 31.7% to $0.48 after the company announced a $2 million stock repurchase plan. POET Technologies Inc. (NASDAQ: POET) gained 31.3% to $4.2750. Jianzhi Education Technology Group Company Limited (NASDAQ: JZ) gained 30% to $1.5657. Rubius Therapeutics, Inc. (NASDAQ: RUBY) jumped 29.4% to $0.2349. Oak Street Health, Inc. (NYSE: OSH) gained 28.4% to $28.99 as CVS Health is reportedly exploring an acquisition of primary care center operator. BTCS Inc. (NASDAQ: BTCS) jumped 28.2% to $1.3199 after the company launched a private beta of its digital asset analytic and staking-as-a-service platform StakeSeeker. Frontline plc (NYSE: FRO) rose 27.1% to $14.40. Frontline announced termination of combination agreement with Euronav. Schmitt Industries, Inc. (NASDAQ:

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Gainers VYNE Therapeutics Inc. (NASDAQ: VYNE) rose 82.2% to $0.35 in pre-market trading after the company said first vitiligo patient was dosed in Phase 1a/b clinical trial of novel BET inhibitor VYN201. Panbela Therapeutics, Inc. (NASDAQ: PBLA) shares rose 45.4% to $0.1178 in pre-market trading after gaining 4% on Monday. Sotera Health Company (NASDAQ: SHC) rose 42.7% to $12.33 in pre-market trading after the company reported settlement of ethylene oxide litigation in Illinois. Oak Street Health, Inc. (NYSE: OSH) shares rose 33.1% to $30.04 in pre-market trading. CVS Health Corp is in talks to buy Oak Street Health, Bloomberg News reported. Versus Systems Inc. (NASDAQ: VS) rose 32.7% to $0.8039 in pre-market trading after jumping over 16% on Monday. Nuwellis, Inc. (NASDAQ: NUWE) rose 23.4% to $11.50 in pre-market trading after gaining 11% on Monday. Nuwellis indicated that preliminary unaudited revenue for the fourth quarter ...

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